Editorial for the Special Issue on “Human Biomonitoring in Health Risk Assessment: Current Practices and Recommendations for the Future”

Christophe Rousselle (1)

1 DER - Direction de l'Evaluation des Risques

In most health risk assessment (HRA) frameworks for chemicals, the default approach for exposure assessment is to estimate the intake from different sources and different routes of exposure. These assessments are often made separately and then added when aggregate exposure scenarios are considered. Various uncertainties are associated with this approach and, depending on the scope of the assessment; it may over- or under-estimate the internal exposure. Having access to data on the internal exposure generated by human biomonitoring gives a complete picture of human exposure and can be used to enhance a chemical risk assessment by providing information on actual human exposure via multiple exposure pathways. An understanding of the contribution that different exposure routes make to the overall exposure (taking into account differences in exposure modifiers, such as age and gender, as well as profession) delivers a starting point for deciding on risk management measures under legislative silos.

Domains: Life Sciences [q-bio]

Christophe Rousselle. Editorial for the Special Issue on “Human Biomonitoring in Health Risk Assessment: Current Practices and Recommendations for the Future”. Toxics, 2023, 11 (2), pp.168. ⟨10.3390/toxics11020168⟩. ⟨anses-03996674⟩