[Foot and mouth disease virus: transmission, pathogenesis, diagnosis and surveillance].

Le virus de la fièvre aphteuse : transmission, pathogenèse, diagnostic et surveillance

Morgan Sarry (1, 2) , Aurore Romey (1) , David Lefebvre (3) , Souheyla Benfrid (1) , Barbara Dufour (4) , Benoit Durand (5, 6) , Gina Zanella (5, 6) , Nick de Regge (3) , Stéphan Zientara (1) , Labib Bakkali Kassimi (1) , Sandra Blaise-Boisseau (1)

1 VIRO - Virologie UMR1161
2 AgroParisTech
3 Sciensano [Bruxelles]
4 EpiMAI USC - Epidémiologie des maladies animales infectieuses
5 Laboratoire de santé animale, sites de Maisons-Alfort et de Normandie
6 EPI - Epidémiologie

Foot-and-mouth disease (FMD) is one of the most contagious viral animal diseases. It is an old disease which still poses a permanent threat of re-emergence for free zones. Foot-and-Mouth Disease Virus (FMDV), a Picornavirus belonging to genus Aphthovirus affects domestic and wild artiodactyls. FMD has a considerable socio-economic impact on agricultural production and trade in endemic regions, but also when incursions occur into FMD free areas, as in Europe in 2001. FMDV is historically one of the most studied viruses. Due to its high genetic and antigenic variability, the absence of cross-immunity between its seven serotypes, its ability to survive in the environment, its high contagiousness, its wide range of hosts and its particular biology, FMDV remains of major interest in animal health and the subject of many research projects. This review presents different aspects of FMDV infection, ranging from basic biology to diagnosis, surveillance and control.

Mots clés: foot-and-mouth disease; FMDV; diagnostics; molecular epidemiology; control

Domaines: Médecine vétérinaire et santé animale

Morgan Sarry, Aurore Romey, David Lefebvre, Souheyla Benfrid, Barbara Dufour, et al.. [Foot and mouth disease virus: transmission, pathogenesis, diagnosis and surveillance].. Virologie, 2022, 26 (5), pp.355-373. ⟨10.1684/vir.2022.0972⟩. ⟨anses-03897910⟩