Serological Evidence of Backyard Pig Exposure to Highly Pathogenic Avian Influenza H5N8 Virus during 2016–2017 Epizootic in France - Archive ouverte HAL Access content directly
Journal Articles Pathogens Year : 2021

Serological Evidence of Backyard Pig Exposure to Highly Pathogenic Avian Influenza H5N8 Virus during 2016–2017 Epizootic in France

(1) , (1) , (1) , (1) , (1) , (1) , (1) , (1) , (1) , (1) , (1)
1

Abstract

In autumn/winter 2016–2017, HPAI-H5N8 viruses belonging to the A/goose/Guandong/1/1996 (Gs/Gd) lineage, clade 2.3.4.4b, were responsible for outbreaks in domestic poultry in Europe, and veterinarians were requested to reinforce surveillance of pigs bred in HPAI-H5Nx confirmed mixed herds. In this context, ten pig herds were visited in southwestern France from December 2016 to May 2017 and serological analyses for influenza A virus (IAV) infections were carried out by ELISA and hemagglutination inhibition assays. In one herd, one backyard pig was shown to have produced antibodies directed against a virus bearing a H5 from clade 2.3.4.4b, suggesting it would have been infected naturally after close contact with HPAI-H5N8 contaminated domestic ducks. Whereas pigs and other mammals, including humans, may have limited sensitivity to HPAI-H5 clade 2.3.4.4b, this information recalls the importance of implementing appropriate biosecurity measures in pig and poultry farms to avoid IAV interspecies transmission, a prerequisite for co-infections and subsequent emergence of new viral genotypes whose impact on both animal and human health cannot be predicted.

Dates and versions

anses-03455289 , version 1 (29-11-2021)

Licence

Attribution - CC BY 4.0

Identifiers

Cite

Séverine Hervé, Audrey Schmitz, François-Xavier Briand, Stéphane Gorin, Stéphane Quéguiner, et al.. Serological Evidence of Backyard Pig Exposure to Highly Pathogenic Avian Influenza H5N8 Virus during 2016–2017 Epizootic in France. Pathogens, 2021, 10 (5), pp.621. ⟨10.3390/pathogens10050621⟩. ⟨anses-03455289⟩

Collections

ANSES
13 View
0 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More