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Subclinical BCG-osis in a Captive Badger (Meles meles) with Lymphoma

Abstract : Subclinical systemic dissemination of Bacillus Calmette-Guérin (BCG) is described in a captive badger (Meles meles) with lymphoma. An adult female European badger was vaccinated per os with BCG and after 8 weeks post-mortem examination identified marked lymphadenomegaly and multinodular hepatic lesions. The histopathology and immunohistochemistry confirmed a multicentric T-cell lymphoma, associated with high BCG bacterial load in numerous tissues. The histology did not identify BCG-associated lesions. The scenario suggested that the T-cell lymphoma likely favoured the dissemination of the BCG ('BCG-osis'). Given that lymphoma is rare in badgers, this neoplasm should not interfere with the efficacy of large-scale vaccination programmes.
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Contributor : Sophie Marchal-Mauer <>
Submitted on : Wednesday, July 21, 2021 - 1:43:02 PM
Last modification on : Friday, July 23, 2021 - 3:31:55 PM




C. Bianco, S. Lesellier, J. Barrat, C. Richomme, M.-L. Boschiroli, et al.. Subclinical BCG-osis in a Captive Badger (Meles meles) with Lymphoma. Journal of Comparative Pathology, Elsevier, 2020, 176, pp.76-80. ⟨10.1016/j.jcpa.2020.02.009⟩. ⟨anses-03294027⟩



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