Clinical Pharmacokinetics 710 and Pharmacodynamics of Colistin, vol.711, 2017. ,
Pharmacokinetics of colistin 712 methanesulphonate and colistin in rats following an intravenous dose of colistin methanesulphonate ,
, The Journal of antimicrobial chemotherapy, vol.53, issue.5, pp.837-877, 2004.
, Stability of Colistin and Colistin, vol.715
, Methanesulfonate in Aqueous Media and Plasma as Determined by High-Performance Liquid 716 Chromatography, vol.47, pp.1364-70, 2003.
,
, Pharmacokinetic/toxicodynamic analysis of colistin-associated acute kidney injury in critically ill 719 patients, Antimicrobial Agents and Chemotherapy, pp.1367-1384, 2017.
Evaluation of colistin as an agent against 721 multi-resistant Gram-negative bacteria, Int J Antimicrob Agents, vol.25, issue.1, pp.11-25, 2005. ,
Pharmacokinetics of 723 colistin and colistimethate sodium after a single 80-mg intravenous dose of CMS in young healthy 724 volunteers, Clinical Pharmacology & Therapeutics, vol.89, issue.6, pp.875-884, 2011. ,
Dynamics of binding and release of the polymyxin antibiotics by tissues, J Pharmacol Exp Ther, vol.726, issue.3, pp.757-65, 1973. ,
Depletion of the residues of 728 colistin and amoxicillin in Turkeys following simultaneous subcutaneous administration. Veterinary 729 research communications, vol.20, pp.175-82, 1996. ,
Renal disposition of colistin in the 731 isolated perfused rat kidney, Antimicrobial agents and chemotherapy, vol.53, issue.7, p.10, 2009. ,
Megalin contributes to kidney 733 accumulation and nephrotoxicity of colistin, Antimicrobial agents and chemotherapy, vol.734, issue.12, pp.6319-6343, 2013. ,
Imaging the distribution 736 of polymyxins in the kidney, Journal of Antimicrobial Chemotherapy, vol.737, p.12, 2014. ,
Cellular uptake and 738 localization of polymyxins in renal tubular cells using rationally designed fluorescent probes. 739 Antimicrobial agents and chemotherapy, vol.59, p.13, 2015. ,
Significant accumulation of 741 polymyxin in single renal tubular cells: a medicinal chemistry and triple correlative microscopy 742 approach, Analytical chemistry, vol.87, issue.3, p.14, 2015. ,
Human oligopeptide transporter 2 (PEPT2) 744 mediates cellular uptake of polymyxins, Journal of Antimicrobial Chemotherapy, vol.745, p.31, 2015. ,
Colistin-induced nephrotoxicity in mice involves the 746 mitochondrial, death receptor, and endoplasmic reticulum pathways, Antimicrob Agents Chemother, vol.747, issue.7, pp.4075-85, 2014. ,
Major pathways of polymyxin-induced 749 apoptosis in rat kidney proximal tubular cells, Antimicrob Agents Chemother, vol.750, p.17, 2015. ,
Whole-body physiologically based pharmacokinetic models. Expert opinion on drug 751 metabolism & toxicology, vol.3, pp.235-284, 2007. ,
, , p.753
, Colistin and Colistimethate sodium (CMS) Model-Predicted Whole-Body Distribution with Measured 754 Tissue:Plasma Concentrations Ratios in Rats. 53 rd Interscience Conference on Antimicrobial Agents 755 and Chemotherapy
, , vol.756, p.19
Evaluation of methods for estimating population pharmacokinetic 757 parameters II. Biexponential model and experimental pharmacokinetic data, Swindle MM, vol.9, p.21, 1981. ,
, Guideline on approach towards harmonisation of withdrawal periods, JECFA. Residue Evaluation of Certain Veterinary Drugs: Joint FAO/WHO Expert Committee on 762 Food Additives, 66th Meeting, vol.764, 2006.
Mathematical modeling and simulation in animal 767 health-Part II: principles, methods, applications, and value of physiologically based pharmacokinetic 768 modeling in veterinary medicine and food safety assessment, Clinical Infectious Diseases, vol.39, issue.5, p.25, 2014. ,
Penetration of antimicrobials to pulmonary epithelial lining fluid and 774 muscle and impact of drug physicochemical properties determined by microdialysis, vol.78, p.26, 2016. ,
, Assay of Colistin and Colistin, vol.777
, Methanesulfonate in Plasma and Urine by Liquid Chromatography-Tandem Mass Spectrometry
Development of a physiologic-based 780 pharmacokinetic model for estimating sulfamethazine concentrations in swine and application to 781 prediction of violative residues in edible tissues, American journal of veterinary research, vol.54, issue.5, pp.1686-93, 2005. ,
Calibration and validation of a physiologically based model for soman 784 intoxication in the rat, marmoset, guinea pig and pig, Journal of applied toxicology : JAT, vol.785, issue.9, p.29, 2012. ,
Tissue distribution 787 of quercetin in rats and pigs, The Journal of nutrition, vol.135, issue.7, p.30, 2005. ,
A model-based approach to assessing the 789 importance of intracellular binding sites in doxorubicin disposition, Molecular Pharmaceutics, vol.790, issue.3, p.31, 2017. ,
Body composition of the 12-week-old pig studied by dissection. 792 Laboratory animal science, vol.47, p.32, 1997. ,
Renal 794 function outcome in unilateral hydronephrosis in newborn pigs. II. Function and volume of 795 contralateral kidneys, J Urol, vol.165, issue.1, pp.205-214, 2001. ,