Lack of experimental evidence to support mcr-1- positive escherichia coli strain selection during oral administration of colistin at recommended and higher dose given by gavage in weaned piglets - Archive ouverte HAL Access content directly
Journal Articles International Journal of Antimicrobial Agents Year : 2017

Lack of experimental evidence to support mcr-1- positive escherichia coli strain selection during oral administration of colistin at recommended and higher dose given by gavage in weaned piglets

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Abstract

In this study, we assessed the selective effect of colistin orally administered to healthy weaned piglets harbouring an intestinal mcr-1-positive Escherichia coli strain. Maximum recommended dose and a higher dose often used in European pig farms were given by gavage. No selection of the mcr-1-positive strain was observed in our controlled conditions whatever the dose. Further investigations in real farming conditions seem necessary.
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anses-01570163 , version 1 (22-06-2020)

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Alexis Viel, Jérôme Henri, Agnès Perrin-Guyomard, Julian Laroche, William Couet, et al.. Lack of experimental evidence to support mcr-1- positive escherichia coli strain selection during oral administration of colistin at recommended and higher dose given by gavage in weaned piglets. International Journal of Antimicrobial Agents, 2017, 51 (1), pp.128-131. ⟨10.1016/j.ijantimicag.2017.04.013⟩. ⟨anses-01570163⟩
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